The first human-tested weight-loss drug that burns calories through creatine-based heat generation, without reducing appetite, has successfully completed its Phase I trial.
Scientists from the Institut Pasteur de Montevideo (IP Montevideo) and the University of the Republic (Udelar) have built on their promising preclinical mouse study to demonstrate that SANA, a small molecule drug that harnesses an unexplored fat-burning pathway, is not only safe for human use but effective.