A new weight-loss compound targeting energy expenditure rather than appetite suppression showed early efficacy in a first-in-human study.
The compound, SANA (MVD1; Eolo Pharma), activates creatine-dependent thermogenesis, a novel approach to obesity and metabolic disease compared to appetite suppression, explained Eolo Pharma CEO María Pía Garat. “To our knowledge, SANA is the only small molecule in clinical development that targets this mechanism, and we expect growing interest in this pathway as our data progresses.”